Despite this low level of evidence, chloroquine or more often hydroxychloroquine are used in daily practice, particularly to treat skin, bone and joint sarcoidosis, as well as hypercalcemia and certain types of uveitis
Chloroquine (CQ) can be an effective treatment for lung sarcoidosis with few side effects, but has not been accepted as standard therapy
Chloroquine phosphate has been reported to be a valuable alternative therapy for cutaneous lesions of sarcoidosis
Chloroquine (CQ) can be an effective treatment for lung sarcoidosis with few side effects, but has not been accepted as standard therapy
We report a case of COVID-19 in a patient with sarcoidosis who was receiving long-term hydroxychloroquine treatment and contracted COVID-19 despite adequate plasma
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CHLOROQUINE was demonstrated by Hunt and Yendt in 1963 to be effective in treating the hypercalcemia of sarcoidosis
Despite this low level of evidence, chloroquine or more often hydroxychloroquine are used in daily practice, particularly to treat skin, bone and joint sarcoidosis, as well as
In this report, we describe the identification of chloroquine as an effective pre- and post-infection antiviral agent for SARS-CoV
Tableau 1
Chloroquine (Oral Route) Chloroquine is used to prevent and treat malaria
Agent selection depends on indication, comorbidities, and anticipated toxicity
Treatment: 1 g (= 600 mg base) once, then 500 mg (= 300 mg base) at 6 h, 24 h and 48 h
Also seek emergency medical attention if you have symptoms of a serious
tunnel vision
The optimal dose is unknown, but a daily dosage of 250–500 mg is most often used
Given the concern regarding ocular toxicity, the maximum dosages of chloroquine and hydroxychloroquine should not exceed 3
In some patients, upper respiratory tract involvement produces hoarseness, nasal obstruction, and recurrent or persistent sinusitis
Sarcoidosis may cause skin problems, which may include: A rash of red or reddish-purple bumps, usually located on the shins or ankles, which may be warm and tender to the touch
It is sold under the brand name Aralen, and it is also sold as a generic medicine
Chloroquine generally refers to chloroquine phosphate (C 18 H 26 ClN 3), a weak base drug that belongs to the first group of quinolone derivatives, the 4-aminoquinolines
Chloroquine with a dose of 200-400mg can be used as an alternative treatment for hypercalcemia and for patients with sarcoidosis who cannot be treated with glucocorticoids
Chloroquine (CQ) is used to combat malaria
For example, both drugs are partially excreted in feces, but the proportions differ slightly—8–10 % for chloroquine and 15–24 % for hydroxychloroquine
Initially 10 mg/kg (max
Initially 620 mg, then 310 mg after 6–8 hours, then 310 mg daily for 2 days, approximate total cumulative dose of 25 mg/kg of base