Symptoms were noted as a pruritic, clustered
Autoimmune progesterone dermatitis (APD) is an immune reaction to endogenous progesterone that can follow exposure to exogenous progesterone
The morphology of cutaneous lesions of APD may include urticarial papules and plaques, a vesicobullous eruption, mucosal lesions, eczematous
Autoimmune progesterone dermatitis (APD) is a rare disorder characterized by recurrent skin manifestations starting during the luteal phase of a
Autoimmune progesterone dermatitis (APD) is a rare hypersensitivity disorder characterized by recurring dermatologic manifestations during the luteal
Patient clinical presentation can vary in severity from mild urticaria to anaphylaxis [5, 6]
Symptoms are varied and include dermatitis, urticaria, asthma, and anaphylaxis
Autoimmune progesterone dermatitis (APD) is a cyclical cutaneous reaction to progesterone, with symptoms that typically begin 3-10 days before the onset of menstrual flow and end 1-2 days into menses
Autoimmune progesterone dermatitis
The case highlights the severe nature of symptoms that progesterone hypersensitivity can present with
The diagnosis should be confirmed using an intradermal skin test to progesterone, during the follicular phase of the menstrual cycle
Symptoms present heterogeneously, which may complicate diagnosis
A 22-year-old nulligravid woman presented with symptoms mistaken for Stevens-Johnson Autoimmune progesterone dermatitis
Progesterone begins to rise 14 days prior
The presence of Autoimmune Progesterone Dermatitis is known to exacerbate the symptoms of other skin conditions, such as cold sores, acne, atopic eczema, and psoriasis, among others, during the premenstrual period
The skin eruptions and respiratory symptoms have not returned since the initiation of this therapy
Symptoms of autoimmune progesterone dermatitis correlate with progesterone levels during the luteal phase of the menstrual cycle [3, 4]
7, 8 APD manifests itself primarily with cutaneous eruptions and rarely causes