Valproic acid causes hyperammonemia

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  • patients with urea cycle enzyme deficiencies (e
  • The incidence of hyperammonemia has
  • Alti-Valproic
  • Valproic acid (VPA) is widely used for the treatment of epilepsy, migraine, and a variety of psychiatric conditions

    Valproic acid, a broad-spectrum anticonvulsant drug, commonly causes elevated ammonia levels, which is usually asymptomatic in most cases

    Although acute VPA intoxication frequently results in mild, self Objective: To report a case of hyperammonemia associated with the interaction between topiramate and valproic acid

    This enzymatic inhibition is why serum ammonia concentrations can elevate in valproic acid toxicity

    Valproic acid-induced hyperammonemia: incidence Valproic acid can cause high levels of ammonia in your blood, which is known as hyperammonemia

    It can be life-threatening and requires immediate medical treatment

    The reported prevalence of valproic acid induced hyperammonemia is as high as 35–45% and seems to be higher in patients with

    5 equivalent of sodium hydroxide

    Valproic acid use has been associated with the induction of hyperammonemic encephalopathy through astrocytic edema, renal

    Abstract

    Upon an increase in blood ammonia levels, glutamine synthetase converts glutamate and ammonia to glutamine

    In some people, hyperammonemia may be clinically significant, resulting in hyperammonemic encephalopathy, which may be severe

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  • Valproic acid causes hyperammonemia
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