Flibanserin women in clinical trials

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  • Abstract and full-text selection was done by 2 independent reviewers
  • Jaspers L, Feys F, Bramer WM, Franco OH, Leusink P, Laan ET, et al
  • 8 USE IN SPECIFIC POPULATIONS 8
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  • Aug 25, 2010 · Patients who have been previously treated with flibanserin

    Despite a need for additional study in diverse populations, flibanserin has demonstrated efficacy with increased female sexual function index (FSFI) total and

    Flibanserin is the first drug in its class to treat FSIAD in premenopausal women

    Data

    1% of placebo Flibanserin is the

    FSFI data pooled from 3 pivotal flibanserin trials in premenopausal women (flibanserin = 1,165; placebo = 1,203) and FSFI data from one complete flibanserin trial in

    Testosterone, buspirone, sildenafil, bupropion, bremelanotide, as well as herbal medications (Herbal vX or Tribulus terrestris) have demonstrated some clinical

    Importance: In August 2015, the US Food and Drug Administration (FDA) approved flibanserin as a treatment for hypoactive sexual desire disorder (HSDD) in premenopausal women, despite concern about suboptimal risk-benefit trade-offs

    Clayton AH, Croft HA, Yuan J, et al

    Developed by the pharmaceutical company Boehringer Ingelheim, flibanserin has been through many vigorous clinical trials

    Flibanserin is the first and only FDA approved medication for the treatment of in women

    1% of placebo Flibanserin is the first medicine of its kind to be approved for the treatment of FSIAD in premenopausal women

    (Clinical Trial) Actual Enrollment : 748 participants Yuan J, Kissling R, Kingsberg SA

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    Debates about the condition aside, Boehringer Ingelheim, the company that originally developed flibanserin, and Sprout, which acquired the drug in 2012, tested the drug in clinical trials in which Introduction: Hypoactive sexual desire disorder (HSDD) is the most prevalent sexual dysfunction in women, previously managed with off-label therapies

    This trial is designed to assess the safety and efficacy of flibanserin in the treatment of premenopausal women with Hypoactive Sexual Desire Disorder (HSDD) that meet standard diagnostic criteria

    Three clinical trials testing flibanserin were consistent in their results

    Standards for clinical trials in sexual dysfunction in women: in United States women revisted Hide glossary Glossary

    It was originally developed as an antidepressant medication by Boehringer Ingelheim, but showed lack of efficacy in trials and was further developed as a hypoactive sexual disorder drug by Sprout A 28-week Safety Study of Flibanserin in Pre- and Postmenopausal Women With Hypoactive Sexual Desire Disorder - Full Text View

    Recommendations for the clinical evaluation of men and women with sexual dysfunction

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