Feb 22, 2021 · Theophylline toxicity has become rare in the 21st century, as the drug has fallen out of favor due to serious life-threatening adverse events, narrow therapeutic window and readily available therapeutic alternatives
Admit patients with theophylline levels higher than 30 mcg/mL
Oral theophylline is used for long-term control of chronic asthma or COPD
Adverse effects related to theophylline use are related directly to serum level of the drug
History Signs and symptoms of theophylline toxicity correlate better with single acute ingestions than with chronic overexposures
Serum theophylline levels will help further refine the risk assessment
The excess circulating catecholamines cause serious clinical effects that are associated with theophylline toxicity
Theophylline is a bronchodilator with a narrow therapeutic index
Last updated on Jan 14, 2024
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theophylline (thee-off-i-lin) Apo-Theo LA, Elixophyllin, breath sounds, respiratory rate, and other symptoms (wheezing, dyspnea, shortness of breath) (See Appendixes I, J, K)
Nevertheless, theophylline remains an important drug: It is still used within the United States to treat apnea and Descriptions
Overdose can also occur slowly over time if your daily doses are too high
It will also investigate early signs of toxicity and how its narrow therapeutic range alters the monitoring of patients receiving these drugs
Bronchodilators are medicines that relax the muscles in the bronchial tubes (air
Theophylline is taken orally and all available brands are modified release preparations
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Cardiac dysrhythmias, Which sign of a serious adverse effect requires the nurse to monitor the patient receiving
Since beta-2 agonists are at least as effective as theophylline as a bronchodilator while having fewer side effects, theophylline has become less popular in
Theophylline level of 20mcg/ml D
Option D: Theophylline toxicity is likely to occur when the serum level is higher than 20 mcg/ml
Nystagmus (involuntary jerking of the eyeball) Seizures
Pregnancy risk category C Heart disease, HTN, liver and kidney dysfuction, and DM