Although digoxin intoxication used to be very common and associated with a high mortality, in recent years its prevalence has substantially
In this report, we analyzed a case series definitively diagnosed as digoxin intoxication in the modern era
In adults and older children, the first signs of toxicity usually include abdominal pain, anorexia, nausea, vomiting, visual disturbances
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0 ng/mL, during a five year period
Chronic digoxin use may lead to accumulation and toxicity
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Be alert for signs of digitalis toxicity
Specific binding occurs in the form of chelating agents for heavy metal poisoning, Digi-Fab for digoxin overdose, hydroxycobalamin for cyanide poisoning, or bioscavenger therapy (human butyryl cholinesterase) for organophosphorus poisoning, 6,7 where the antidote enables the formation of inert complexes 8 that are then eliminated from the body A CASE OF DIGOXIN TOXICITY
Digoxin-specific antibody
0 ng/mL]) obtained at appropriate
Digoxin has a narrow therapeutic index and chronic toxicity is more likely in the elderly and those with renal impairment
[2] While
The consensus identifies a straightforward approach to dosing immune antibody fragments according to the presence or absence of signs of life-threatening toxicity
4%), followed by tachycardia (29
Increase force and efficiency of myocardial contraction decrease HR