SUmmarize dose-response monitoring for patients on mebendazole therapy
Mebendazole is a carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5
Synthesis of benzimidazole derivatives 5a-f (series B)
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HCl], a new stable salt of mebendazole (MBZ), has been
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Mebendazole hydrochloride [(5‐benzoyl‐1H‐benzimidazole‐2‐yl)‐carbamic acid methyl ester hydrochloride, MBZ·HCl], a new stable salt of mebendazole (MBZ), has been synthesized and characterized
• Formation of a R 2 2 (8) supramolecular synthon between mebendazole and nitrate
; 2 CNRS, LCC (Laboratoire de Chimie de Coordination), Université de Toulouse, UPS, INPT, 205 Route
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Bioorganic & Medicinal Chemistry 11 (2003) 4615–4622 Synthesis and Antiparasitic Activity of Albendazole and Mebendazole Analogues§ Gabriel Navarrete-Va´zquez,a,* Lilia´n Ye´pez,b Alicia Herna´ndez-Campos,a Amparo Tapia,b Francisco Herna´ndez-Luis,a Roberto Cedillo,c Jose´ Gonza´lez,a Antonio Martı´nez-Ferna´ndez,d Mercedes
Results indicate that two Abz analogues and two Mbz analogues were as active as Metronidazole against G
However, 4'-azidothymidine (6a) retained its activity against HIV mutants which were resistant to AZT
Using the anilines 6a-6j as the starting materials, the main chain compounds 10a-10j were synthesized via four steps
The magenta dashed lines represent the hydrogen bonds between Mebendazole and hinge
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It was obtained from recrystallization of MBZ forms A, B, or C in diverse solvents with the addition of methyl sulfonic acid solution