Divalproex was initiated at 15 mg/kg/day and titrated over 12 days to a maximum dosage
This 47-week, randomized, double-blind study compared flexibly dosed olanzapine (5
DOI: 10
Schizophrenic patients (n=249; aged 18-63 yrs) were randomly assigned to receive olanzapine monotherapy, risperidone monotherapy, divalproex plus olanzapine, or
OBJECTIVE: Few double-blind trials have compared longer-term efficacy and safety of medications for bipolar disorder
This study compares the clinical, health-related quality of life (HRQL), and
OBJECTIVE: The effects of olanzapine and divalproex for the treatment of mania were compared in a large randomized clinical trial
During the study, the dosage of divalproex or olanzapine could be lowered to improve tolerability
Olanzapine and risperidone Every year in the U
Background: Divalproex sodium is a mood stabilizer used in the United States for the treatment of acute mania associated with bipolar disorder
4 to 1
METHOD: A manual and computer (MEDLINE) search was performed for combinations of the most commonly used mood-stabilizing agents
6 In a meta-analysis of four randomised controlled trials (RCT) (1330 patients), OFC therapy significantly reduced the severity of depressive symptoms when compared with a placebo (odds ratio (OR): 0
1016/S0924-977X(01)80532-0 Corpus ID: 19787298; Olanzapine versus divalproex sodium for the treatment of acute mania and maintenance of remission: A 47-week study @article{Tohen2001OlanzapineVD, title={Olanzapine versus divalproex sodium for the treatment of acute mania and maintenance of remission: A 47-week
The difference in weight gain Olanzapine–valproate combination versus olanzapine or valproate monotherapy in the treatment of bipolar I mania: a randomized controlled study in a Chinese population group Lei Xu,1 Yunrong Lu,1 Ying Yang,1 Yanping Zheng,1 Fang Chen,1 Zheng Lin2 1Department of Geriatric Diseases, 2Department of Psychiatry, Second Affiliated
T1 - The safety and early efficacy of oral-loaded divalproex versus standard-titration divalproex, lithium, olanzapine, and placebo in the treatment of acute mania associated with bipolar disorder
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