Phenytoin dosing ppt

Zyprexa similar drugs
  • 8,10 Phenytoin is completely absorbed
  • Children older than 6 years of age—300 mg per day
  • Knowledge of its pharmacokinetic
  • The efficacies
  • Phenytoin overdose has been described (101 A)
  • Absorption
  • The standard regimen in Japan is 22
  • Only use intravenous administration when these options are not feasible and where cardiac monitoring is available

    Total phenytoin level: The target total phenytoin level is ~10-20 ug/mL (and ideally 15-20 ug/mL in status epilepticus)

    Background

    Therapeutic drug monitoring of phenytoin is necessary to ensure dosage delivery is at therapeutic levels

    Phenytoin is a hydantoin compound related to the barbiturates that are used for the treatment of seizures

    Health & Medicine

    Calculates phenytoin loading doses, maintenance dose and correct levels based on serum albumin

    Uses Warnings Before taking Dosage Side effects Interactions What is phenytoin? Phenytoin is an anti-epileptic drug, also called an

    The results suggest that a measured free phenytoin should be obtained where possible to guide phenytoin dosing

    Summarize the interprofessional team's coordinated

    Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon)

    The following equation is a simple pharmacokinetic equation to estimate a loading dose or resulting serum concentration of a drug

    This finding suggests that once daily dosing of phenytoin is reasonable and that the time period to achieve a new serum level after a dosing change may take 2 weeks or more

    It may also be used in the prevention of seizures following head trauma, and in ventricular arrhythmias

    Therapeutic level 10-20mg/L

    The recommended starting dose for adult patients who have received no previous treatment is one 100-mg DILANTIN (extended phenytoin sodium capsule, USP) by mouth three times daily

    However, fentanyl exhibits vastly different properties

    After another 6 hours the serum phenytoin

    The metabolism of phenytoin to the major metabolite, 5-(p-hydroxyphenyl)-5-(phenylhydantoin, is saturable, giving rise to a non linear dose-serum concentration relationship

    The rate of intravenous phenytoin administration should not exceed 50 mg/minute in adults and 1 to 3 mg/kg/minute (or 50 mg/minute, whichever is slower) in pediatric patients because of the risk of severe hypotension and cardiac arrhythmias

    It is an effective anticonvulsant for the chronic treatment of tonic-clonic (grand mal) or partial seizures and the acute treatment of generalized status epilepticus ( Table 10-1 )

    05 ml/kg) IV

    Single daily dosage (phenytoin sodium, extended): If seizure control is established with divided doses of three 100-mg extended phenytoin sodium capsules per day, once-a-day dosage with 300 mg PO may be considered

    Phenytoin is an antiepileptic drug which can be used in the treatment of epilepsy

    [4] Mechanism of Action

    There is no caveat included for the caution regarding the use phenytoin or carbamazepine as a second-line agent if a channelopathy is suspected (page 11) and further, for the incorporation of genetic testing in the treatment

    Medications are an important part of the management of patients with kidney disease

    There is a possibility of

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