Grapefruit juice and colchicine

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  • Conclusion: The data suggest that GFJ may augment colchicine
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  • Avoid the use of grapefruit products while taking colchicine
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  • 6 mg 1 or 2 times a day
  • 2
  • This study will evaluate the effect of multiple daily consumptions of grapefruit juice on the pharmacokinetic profile of a single 0

    If you miss your dose of colchicine, take your dose as soon as you remember

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    PurposeTo investigate the potential interaction between grapefruit juice (GFJ) and the oral microtubule polymerization inhibitor colchicine, a P-gp and CYP3A4

    Colchicine tablets are taken in short courses of treatment to relieve the pain of a gout attack

    High levels of medication in your body raise your risk of unwanted side effects

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    Grapefruit juice and its constituents augment colchicine intestinal absorption: potential hazardous interaction and the role of p-glycoprotein

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    An attack of gout occurs when uric acid causes inflammation (pain, redness, swelling, and heat) in a joint

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  • Grapefruit juice and colchicine
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